We seek a highly collaborative Scientist/ Senior Scientist, Human Genetics in statistical genetics and/or quantitative genetics to join Biogen’s Human Genetics group.

The Scientist/Senior Scientist, Human Genetics, will be responsible for providing genetics and genomics expertise to the R&D organization with a focus on developing and applying cutting-edge genetic approaches to support early target discovery and validation.

Biogen has made substantial investments into generating genetic and omics data from population-scale human research cohorts as well as participants of our clinical trials. The Senior Scientist will focus on how to best leverage these resources towards discovering new and improved treatments for degenerative brain diseases including Multiple Sclerosis, Amyotrophic Lateral Sclerosis, Parkinson’s disease, and Alzheimer’s disease, among others. This includes conducting large-scale genome-wide association analyses and/or conducting post-GWAS analyses for target identification and validation.

What You’ll Do
You will work independently and creatively in a cross-disciplinary environment to:

Design innovative research studies and execute studies on a HPC and cloud computing environments
Lead the analysis of genetic studies of CNS disease risk and progression
Apply a wide array of computational genomic approaches (hands-on)
Keep abreast of, and apply, state-of-the-art methods in statistical genetics
Integrate genetics with omics and public/proprietary human molecular evidence
Establish and mature therapeutic hypotheses and propose new drug discovery programs
Collaborate within cross-functional teams to move pipeline programs forward
Communicate findings to technical and non-technical audiences
Drive and contribute to scientific manuscripts

Who You Are
You have a strong quantitative and analytical background in human genetics and are interested in applying your skills to drive drug discovery. You will have outstanding written & oral communication skills.

Required Skills

Ph.D., M.D./Ph.D. or M.D. degree with a focus on Statistical Genetics, Genetic Epidemiology, Human Genetics, Computational Biology, Bioinformatics, or a related field
Strong understanding of biostatistics & statistical genetics methods
Experience analyzing human genetic data (e.g. genotypes, exomes, and/or genomes)
Expertise in statistical software & computer programming (e.g., Plink, R, python)
Strong self-motivation and the ability to work within a cross-disciplinary team

Preferred Skills

Scientific background in neurology/neuroscience, immunology and/or biology
Expertise in working with large real world data sets, including electronic medical records (EMRs) or image data
Experience analyzing longitudinal data and/or quantitative trait loci (QTLs)

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About Biogen

Our mission to find therapies for neurological and rare diseases is a unique focus within our industry and this shared purpose is what connects us?as?a team. We work together to overcome obstacles and to follow the science. We are resilient as we strive to make an impact on our patients’ lives and on changing the course of medicine. Together, we pioneer. Together, we thrive.

Connections working at Biogen

https://careers.esd.org/jobs/17999496/scientist-sr-scientist-genetic-epidemiology

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